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Our research focuses on studying the stability and dynamics of biomolecular folding and interactions to uncover the molecular mechanisms underlying biological and pathological processes. We develop and apply cutting-edge single-molecule manipulation and detection techniques to achieve these goals. Additionally, we aim to create single-molecule diagnostics for high-throughput, multiplexed biomarker detection. Our highly interdisciplinary research integrates expertise in chemistry, biochemistry, biophysics, DNA nanotechnology, biomolecular engineering, and molecular biology.

Prof. Shrestha is actively looking for motivated graduate students (from the class of Fall 2024) to work on bioanalytical/biochemical research using modern single-molecule techniques. Shrestha Lab particularly values your passion and curiosity! 

• For prospective graduate students, you can apply through the graduate program in the Department of ����vlog�ٷ���� chem/graduate-program/admission. To discuss joining our team, send email at prakash_shrestha@uky.edu
• For prospective undergraduate students, you can apply through the undergraduate research program in the Department of ����vlog�ٷ���� chem/undergraduate-program. To discuss joining our team, send email at prakash_shrestha@uky.edu
• For postdoctoral position, please send an email including a cover letter and your CV to  prakash_shrestha@uky.edu

Instructor/Scientist: 2022-2024, Harvard Medical School, Wyss Institute, and Boston Children’s Hospital

Postdoctoral fellow: 2018-2022, Harvard Medical School, Wyss Institute, and Boston Children’s Hospital

• NIH K25 Award (2024)
• Travel Award, Biophysical Society Annual Meeting (2020)
• Graduate Students Senate Domestic Travel Award, Kent State University (2017)
• Taylor Graduate Research Award, Department of ����vlog�ٷ���� and Biochemistry, Kent State University (2017)
• Best Poster Award, Student Affiliates of the American Chemical Society (SAACS), Department of ����vlog�ٷ���� and Biochemistry, Kent State University (2016)
• University Fellowship, Kent State University (2015/2016)
• Merit Scholarship, Department of ����vlog�ٷ���� and Biochemistry, Kent State University (2012)
• Nepal Vidhya Bhushan Medal B, Ministry of Education, Government of Nepal (2011)
• Gold Medal, Central Department of ����vlog�ٷ����, Tribhuvan University, Kathmandu, Nepal (2010)