/ en /seminar-Summer2016-Cardin <span>X-ray Crystallography and infrared transient spectroscopy with nucleic acid crystals</span> <span><span>cagi232</span></span> <span><time datetime="2016-05-03T09:58:06-04:00" title="Tuesday, May 3, 2016 - 09:58 am">Tue, 05/03/2016 - 09:58 am</time> </span> <div><p>Christine Cardin will be presenting a Nietzel Visiting Distinguished Faculty Program Seminar titled, <em>"X-ray Crystallography and infrared transient spectroscopy with nucleic acid crystals."</em></p> <p><strong>Abstract</strong>: Photoactive ruthenium polypyridyl complexes attract worldwide attention because of their potential applications in cancer chemotherapy and because they provide useful tools for studying the fundamentals of electron transfer in DNA. In this talk, the structures of several ruthenium complexes bound to several oligonucleotides will be described. The recent transient infrared spectroscopy (TRIR) study of the photooxidizing [Ru(TAP)₂dppz]²⁺ complex crystallized with the decamer duplex d(TCGGCGCCGA)₂ has provided an insight into the earliest steps in guanine photooxidation and hence, DNA damage.</p> <p><img alt height="2200" src="/sites/default/files/05-13_Cardin_Seminar.jpg" width="1700" loading="lazy"></p> </div> <div> <div class="field-label font-bold inline-block">Date: </div> <div class="field-items inline-block"> <div><time datetime="2016-05-13T20:00:00Z">Friday, May 13, 2016 - 04:00 pm</time> - <time datetime="2016-05-13T20:50:00Z">Friday, May 13, 2016 - 04:50 pm</time> </div> </div> </div> <div> <div class="field-label font-bold inline-block">Location: </div> <div class="inline-block">CP - 114</div> </div> <div> <div class="field-label font-bold inline-block">Tags/Keywords: </div> <div class="field-items inline-block"> <div><a href="/tag/crystallography" hreflang="en">crystallography</a></div> <div><a href="/tag/spectroscopy" hreflang="en">spectroscopy</a></div> <div><a href="/tag/christine-cardin" hreflang="en">christine cardin</a></div> <div><a href="/tag/glazer-group" hreflang="en">glazer group</a></div> <div><a href="/tag/nietzel" hreflang="en">Nietzel</a></div> </div> </div> <div> <div class="field-label font-bold inline-block">Event Series: </div> <div class="field-items inline-block"> <div><a href="/event-type/summer-2016-chemistry-department-seminar" hreflang="en">Summer 2016 ÌÇÐÄvlog¹Ù·½Èë¿Ú Department Seminar</a></div> </div> </div> <ul class="links inline"><li><a href="/seminar-Summer2016-Cardin" rel="tag" title="X-ray Crystallography and infrared transient spectroscopy with nucleic acid crystals" hreflang="en">Read more<span class="visually-hidden"> about X-ray Crystallography and infrared transient spectroscopy with nucleic acid crystals</span></a></li></ul> Tue, 03 May 2016 13:58:06 +0000 cagi232 309021 at